Download Advances in Molecular and Cellular Endocrinology by Derek Leroith (Eds.) PDF

By Derek Leroith (Eds.)

Quantity 2 has excited about facets of the pituitary gland either anterior (growth hormone and prolactin receptors, and GH motion) and posterior (vasopressin) pituitary. additionally, thyroid melanoma and steroidogenic enzymes and precocious puberty are coated. eventually, the "hot subject matters" contain leptin and development issue signaling.

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C. (1995). Mapping of the cytoplasmic domain of the human growth hormone receptor required for the activation of JAK2 and STAT proteins. J. Biol. Chem. 270, 21326-21330. , & Horn, F. (1996). Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp 130. II. Src homology SH2 domains define specificity of stat factor activation. J. Biol. Chem. 271, 12999-13007. F. (1996). Saturation mutagenesis of the WSXWS motifofthe erythropoietin receptor.

Amino acids of the human growth hormone receptor that are required for proliferation and JAK-STAT signaling. Mol. Endocrinol. 9, 303-311. A. (1994). Structural and functional basis for hormone binding and receptor oligomerization. Curr. Opin. Cell. Biol. 6, 163-173. A. (1996). Binding in the growth hormone receptor complex. Proc. Natl. Acad. Sci. USA 93, 1-6. A. (1995). Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/STAT5. J. Biol. Chem. 270, 9448-9453.

Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines. J. Biol. Chem. 270, 13133-13137. , & Taniguschi, T. (1995). Activation of STAT5 by interleukin 2 requires a carboxy-terminal region of the interleukin 2 receptor 13chain but is not essential for the proliferative signal transmission. Proc. Natl. Acad. Sci. USA 92, 5482-5486. , & Billestrup, N. (1996). Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene. Mol. Endocrinol. 10, 652-660.

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