Download Advances in Surgical Pathology: Endometrial Carcinoma by Anna Sienko PDF

By Anna Sienko

Part of the preferred Advances in Surgical Pathology sequence, this quantity is a concise, up-to-date assessment of the pathological features of endometrial melanoma. It emphasizes the histologic correlation, medical administration, and therapy of endometrial melanoma, and lines present and rising options within the box. The booklet offers a source for the well timed updates in wisdom which are invaluable for day-by-day perform, for present credentialing, and for the self-assessment modules for recertification (MOC).

A unfastened spouse website positive aspects absolutely searchable textual content in addition to over a hundred thirty full-color images.

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Extra resources for Advances in Surgical Pathology: Endometrial Carcinoma

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5 Villoglandular Variant This variant is characterized by the presence of slender, finger-like papillae lined by columnar cells with low-grade cytologic atypia. The nuclei of the neoplastic cells preserve their polarity in relation to the basement membrane of the epithelium, and the contour of the papillae is smooth (Fig. 4-7). 14 Secretory Variant This rare variant of endometrioid adenocarcinoma is usually seen in postmenopausal patients, although it can also occur in premenopausal patients, with or without a history of endogenous or exogenous progestational effect.

34 Section II • Histopathology FIGURE 3-18: Squamous metaplasia. 25 However, ciliated cells also can be noted within glands in endometrium stimulated by unopposed estrogen5 or in inactive endometrium (unpublished personal observation). Ciliated cells may have eosinophilic, basophilic, or pale cytoplasm. The nuclei are stratified, oval, or round, with even distribution of the chromatin and small nucleoli (Fig. 3-19). The round nuclei with nucleoli in ciliated metaplasia should not be mistaken for the atypia of hyperplasia.

2006;106:804–811. 21. Baak JP, Mutter GL, Robboy S, et al. The molecular genetics and morphometry-based endometrial intraepithelial neoplasia classification system predicts disease progression in endometrial hyperplasia more accurately than the 1994 World Health Organization classification system. Cancer. 2005;103:2304–2312. 22. Lacey JV, Mutter GL, Nucci MR, et al. Risk of subsequent endometrial carcinoma associated with endometrial intraepithelial neoplasia classification of endometrial biopsies.

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